The effect of preparations from whole blood (dry plasma) on the animal organism was studied. In the course of our research, 2 groups of animals with 15 animals in each of 10 days of age were formed on the basis of analogues. The first group of animals was given dry plasma mixed with mixed feed (based on 5% of the feed weight), the second group was the control one and received no additives. Piglets of both groups were kept in the same sanitary and hygienic conditions, every day they evaluated the clinical status of animals, took into account morbidity, mortality, mortality, weighed, and blood was taken for morphological and biochemical blood tests. It was found that in the group of animals that used dry plasma, they gained weight more intensively during 1.5-2 months than the pigs of the control group, a low percentage of the incidence of pathologies from the gastrointestinal tract and respiratory system was established (2-4% whereas in the control group - 9-14%), higher weight gain (10-15%), mortality was not observed (whereas in the control group 2 pigs fell on the background escherichiosis and salmonellosis). Piglets of the experimental group were mobile, active, appetite expressed. In the control group, in addition to the above morbidity and mortality, low daily weight gain was observed (350 grams per day), some animals were inactive, lethargic, and a decrease in appetite was observed (50% of the animals of the group). The results of laboratory studies showed that the use of dry plasma in the diet of piglets contributes to the fastest restoration of blood counts to physiological norm. So already on the 15th day after giving dry plasma, the number of red blood cells was in the range 6.0 ± 0.42 x 10¹² / l, platelets 180.5 ± 1.3 x 10⁹ / l, the amount of hemoglobin in the range of 90.5 ± 0, 95 g / l, white blood cells 15.33 ± 0.62 x 10⁹ / l, a decrease in ESR to 1.55 ± 0.07 mm / h was observed, the amount of total protein was in the range of 64.55 ± 2.12 g / l , the level of albumin is 18.89 ± 3.52 g / l, the activity of the enzymes AsAT, AlAT 0.55 ± 0.06 μkat / l and 0.66 ± 0.03 μkat / l, respectively, the activity of alkaline phosphatase was at level 1, 01 ± 0.12 μkat / l, bilirubin 7.51 ± 0.168 mmol / l, which indicates an improvement in metabolism, in the first The next step is protein metabolism.

Feeding dry plasma increases the average daily growth (500 grams per day), positively affects the improvement of the overall metabolism (especially protein metabolism), which leads to an increase in the body's resistance and, as a result, a decrease in the incidence and mortality of animals.

Key words: antibiotics, antibiotic resistance, piglets, prebiotics, probiotics, synbiotics, blood products, dry blood plasma.