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Prophylactic of gastroenteritis in suckling piglets using phytobiotic EXTRACT™ 6930

The main task of specialists of veterinary medicine is to improve preservation and viability of piglets in the conditions of 
industrial cultivation. 
The  purpose  of  this  research  was  to  determine  the  prophylactic  effectiveness  of  phytobiotic  EXTRACT™  6930  for 
gastroenteritis in suckling piglets.  
The research were performed on PAP “Agroprodservice”. The object of the research were clinically healthy piglets (Landrace 
breed) aged 10 days, selected on the basis of analogues, formed in the control (n=134) and experimental groups (n=137). 
Experimental group of piglets from the age of 10 to 28 days received additionaly feed made phytobiotic EXTRACT™ 
6930 (Pancosma S.A., Switzerland) at dose of 150 g/t in accordance with the recommendations in the guideline to use. 
The material for the study was animal blood of control and experimental groups, obtained from the vena cava cranialis 
on the 10 th, 20th and 28 days of life. On the 10th day of life in piglets of the control and experimental groups clinical symptoms of gastroenteritis are not found. 
As a result of observations during the research in part of piglets in the control (28.3 %) and experimental (18.9 %) 
groups on the 18-20th days of life we have found clinical symptoms of gastroenteritis (diarrhea at normal body temperature 
38-40 °C). Harder disease runs in the control group of animals. 
It should be noted that during experiment from 134 pigs from control group 38 piglets      (28.3 %) had gastroenteritis, of 
whom 11 died (8.2 %). In the experimental group (n=137), the percentage of sick animals was 18.9 % (26 animals), 1.4 % 
(2 animals) died. 

It was established that the use of phytobiotic EXTRACT™ 6930 reduced on 9.4 % the morbidity of gastroenteritis in 
piglets and 6.8 % increased their survival, comparing to control group of animals. 
The development of the gastroenteritis in piglets due to a decrease in the mother's milk of maternal antibodies, because 
of this developing a second phase of age immune deficiency. 
The use of phytobiotic EXTRACT™ 6930 for suckling piglets had a positive influence on erythrocytopoiesis. In particu-
lar, on the 28th day of life the blood erythrocyte rate in piglets of experimental group significantly (p<0.05) increased per 
7.1 %, while in control group significantly (p<0.05) decreased per 5.2 %, and the difference between the end of the experi-
ment was 9.1 % (p<0.01).  
The concentration of hemoglobin in the blood of control group of piglets at the end of the experiment tended to decrease, 
while in experimental piglets significantly (p<0,05) increased and was 6.3 % higher comparing to control group of animals. 
During the experiment, hematocrit value in the control group of piglets tended to decrease, while in experimental group 
is increased. On the 28th day of animal’s life hematocrit was significantly (p<0.01) higher on 9.5 % in the blood of experi-
mental piglets, comparing to control group of animals. 
The use of phytobiotic EXTRACT™ 6930 had positive influence on erythrocytopoesis and hemoglobin synthesis in an-
imals, as indicated by the number of erythrocytes, concentration of hemoglobin and hematocrit in blood of suckling piglets 
from experimental group. 
The use of phytobiotic EXTRACT™ 6930 was significantly (p<0,05) increased total serum protein, while in control pig-
lets was decreased and on 28th
 day was per 6.7 % (p<0,001) lower comparing to experimental group. 
The increase of total protein due to albumins, since in piglets of experimental group on 28th day their level was signifi-
cantly higher per 12.5 (p<0.05) і 12.2 % (p<0.01), comparing to beginning of the experiment and to control group. 
Since all albumins synthesized in hepatocytes, then use of phytobiotic EXTRACT™ 6930 has a positive effect on the 
formation of protein synthesis in liver. 
The activity of AST and ALT genetically determined and is closely related to the level of productivity of animals. There-
fore, high serum aminotransferase activity in piglets of control and experimental groups at the beginning of the experiment 
due to enhanced metabolic processes related to protein synthesis for muscle tissue build. 
In the experimental group of piglets the activity of ALT significantly (p<0.001) decreased on 28th day and was lower per 
25.6 % comparing to 10th day and per 14.2 % (p<0.01) comparing to control group of animals. 
The activity of  AST  also decreased in the experimental  group of piglets on 28th day and  was significantly lower by 
41,1% (p<0,001) comparing to 10th day of life. In the control group this parameter on 28th day was also significantly (p<0.001) lower, but only per 25.7 % comparing to 
beginning of the experiment. 
The use of EXTRACT™ 6930 for piglets decreased serum aminotransferases activity comparing to beginning of the ex-
periment. This indicates a stabilization of cell structures of hepatocytes. 
Prospects  for  further  research  will  to  determine  the  therapeutic  effectiveness  of  phytobiotic  EXTRACT™  6930  for 
gastroenteritis in weaned piglets. 
Key words: suckling piglets, phytobiotic, gastroenteritis, erythrocytes, hemoglobin, hematocrit, total protein, albumins, 
enzymes. 
 

 

 

1. Hvorobi svinej [tekst]: pіdruchnik [dlja vishhih navch. zakl.] / V.І. Levchenko, V.P. Zajarnjuk, І.V. Papchenko ta іn.; 
Za red. V.І. Levchenka і І.V. Papchenka. – Bіla Cerkva, 2005. – 168 s. 
2.  Kocjumbas  І.Ja.  Problemi  vikoristannja  antimіkrobnih  preparatіv  dlja  stimuljuvannja  rostu  produktivnih  tvarin  ta 
al'ternativi  jіh  zastosuvannju  /  І.  Ja.  Kocjumbas,  V.M.  Gunchak,  T.І.  Stec'ko  //  Naukovo-tehnіchnij  bjuleten'  Іnstitutu 
bіologіjі  tvarin  і  Derzhavnogo  naukovo-doslіdnogo  kontrol'nogo  іnstitutu  vetpreparatіv  ta  kormovih  dobavok.  –  2013.  – 
Vip. 14, № 3–4. – S. 381–389. 
3. Effects of adding essential oil to the diet of weaned pigs on performance, nutrient utilization, immune response and in-
testinal health / P. Li, X. Piao, Y. Ru et al. // Asian-Aust. J. Anim. Sci. – 2012.  – Vol. 25, No. 11. –  P. 1617–1626.  
4. Hanczakowska E. Effect of herbal extracts on piglet performance and small intestinal epithelial villi / E. Hanczakow-
ska, M. Swiatkiewicz // Czech J. Anim. Sci. – 2012. – 57 (9). – P. 420–429. 
5. Alternatives to antibiotic growth promoters in prevention of diarrhoea in weaned piglets: a review / H. Vondruskova, 
R. Slamova, M. Trckova et al. // Veterinarni Medicina. –  2010. – 55 (5). – P. 199–224.  
6. Podobed L.I. Natural'naja rastitel'naja kormovaja dobavka «Jekstrakt» v kormlenii sel'skohozjajstvennyh zhivotnyh i 
pticy / L.I. Podobed, A.T. Stoljar, A.A. Arhipov. – Odessa: Pechatnyj dom, 2007. – 48 s. 
7.  Povod  M.G.  Dinamіka  іnter’jernih  pokaznikіv  svinej  pri  viroshhuvannі  v  umovah  glibokojі  nezmіnnoi'  pіdstilki  /  
M.G. Povod, V.O. Baranchenko, E.V. Jesіna // Vіsnik Dnіpropetrovs'kogo agrarnogo unіversitetu. –2008. – №2. – S. 121–125. 
8.  Veterinarna  klіnіchna  bіohіmіja    [tekst]:  pіdruchnik  /  V.І.  Levchenko,  V.V.  Vlіzlo,  І.P.  Kondrahіn  ta  іn.;  za  red. 
V.І. Levchenka і V.L. Galjasa. – Bіla Cerkva, 2002. – 400 s. 
9. Lodjanov V.V. Biohimicheskie pokazateli krovi svinej specializirovannyh tipov [Elektronnij resurs] / V.V. Lodjanov, 
E.A.  Ganzenko  //  Nauchnyj  zhurnal  KubGAU.  –2014.  –  №97  (3).  –  S.  1367–1376.  Rezhim  dostupu: 
http://ej.kubagro.ru/2014/03/pdf/93.pdf 
10.   Jefіmov V.G. Bіohіmіchnі pokazniki krovі svinej na rіznih etapah viroshhuvannja za vplivu vіtamіnu E і selenu / 
V.G. Jefіmov // Naukovo-tehnіchnij bjuleten' DNDKІ vetpreparatіv ta kormovih dobavok і ІBT. – 2015. – Vip. 16, № 2. – 
S. 23–29. 
11.  Goral's'kij  L.P.  Fermentativna  aktivnіst'  sirovatki  krovі  porosjat  pershogo  mіsjacja  zhittja  /  L.P.  Goral's'kij, 
І.І. Panіkar // Vіsnik Zhitomirs'kogo nacіonal'nogo agroekologіchnogo unіversitetu. – 2014. – № 1 (1). – S.111–118.