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Yeast fungi of the genus Malassezia in dermatological diseases in animals
The relevance of a comprehensive study of yeast fungi of the genus Malassezia and the development of modern methods for the diagnosis of diseases caused by small domestic animals. Infectious diseases of small domestic animals caused by yeasts have become a high priority in recent years among the problems of veterinary mycology. However, issues of diagnosis, therapy and prevention of yeast infections in small pets remain poorly understood. Difficulties in diagnosing Malassezia infections lead to the fact that in most cases these diseases remain undiagnosed, sick animals do not receive adequate therapy. Therefore, there is a clear need to develop affordable and practical diagnostic algorithms. Depending on the severity and location of the lesion, systemic or local antifungal drugs are used in combination with symptomatic treatment: antihistamines, antipruritic drugs. If necessary, antibiotic therapy is used and in case of using systemic antifungal drugs, hepatoprotectors are prescribed. Malassezia-associated dermatitis in animals is usually a secondary problem due to an underlying skin disease, such as allergic dermatitis (including atopic canine dermatitis and flea dermatitis), recurrent bacterial pyoderma, and endocrine diseases (especially hypothyroidism). The diagnosis of Malassezia-associated dermatitis should be based on a combination of clinical manifestations and microbiological analysis. Treatment is usually selected depending on such factors as: form (localized or generalized), general state of health of the animal, the main primary disease. A review of literature sources on this issue. The characteristics of different species of the genus Malassezia, which are present on the skin of domestic animals and have an etiological significance in the occurrence of diseases of small domestic animals. The localization of yeast fungi on the body of sick animals is described. In Ukraine, these diseases have not been purposefully studied, and the awareness of veterinarians and humane physicians about them remains unsatisfactory.
Key words: yeast, fungi of the genus Malassezia, dermatitis, otitis, infection.
- Boekhout, T., Gueho-Kellerman, E., Mayser, P., Velegraki, A. (2010). Malassezia and the skin. Berlin: Springer, 319 p.Doi:10.1007/978-3-642-03616-3.
- Gaitanis, G., Magiatis, P., Hantschke, M., Bassukas, I., Velegrakid, A. (2012). The Malassezia Genus in Skin and Systemic Diseases Clinical Microbiology Reviews. Vol. 25(1), pp. 106–141.Doi:10.1128/CMR.00021-11
- Mauldin, E.A., Scott, D.W., Miller, W.H., Jr, Smith C.A. (1997). Malassezia dermatitis in the dog: A retrospective histopathological and immunopathological study of 86 cases (1990–1995). Vet Dermatol. Vol. 8, pp. 191–202.Doi:10.1046/j.1365-3164.1997.d01-15.x
- Bond, R., Saijonmaa-Koulumies, L.E.M., Lloyd, D.H. (1995). Population sizes and frequency of Malassezia pachydermatis at skin and mucosal sites of healthy dogs. J Small Anim Pract. Vol. 36, pp. 147–150. Doi: 10.1111/ j.1748-5827.1995.tb02865.x
- Miller, W.H., Griffin, C.E., Campbell, K.L. (2013). Muller & Kirk’s Small Animal Dermatology, 7th ed., St. Louis, Missouri: Elsevier. pp. 243–249. Doi:10.1111/avj.12088
- Nardoni, S., Dini, M., Taccini, F., Mancianti, F. (2007). Occurrence, distribution and population size of Malassezia pachydermatis on skin and mucosae of atopic dogs. Vet Microbiol. Vol. 122(1-2), pp. 172–177. Doi: 10.1016/j.vetmic.2006.12.023
- Miller, W.H., Griffin, C.E., Campbell, K.L. (2013). Muller & Kirk’s Small Animal Dermatology, 7th ed., St. Louis, Missouri: Elsevier. pp. 741—766. Doi:10.1111/ avj.12088
- Guillot, J., Bond, R. (2020). Malassezia Yeasts in Veterinary Dermatology: An Updated Overview. Doi:10.3389/fcimb.2020.00079).
- Cavana, P., Peano, A., Petit, J.Y. (2015). A pilot study of the efficacy of wipes containing chlorhexidine 0.3%, climbazole 0.5% and Tris-EDTA to reduce Malassezia pachydermatis populations on canine skin. Vet Dermatol. Vol. (26), pp. 278–261. Doi:10.1111/vde.12220
- Berger, D.J., Lewis,T.P., Schick, A.E., Stone, R.T. (2012). Comparison of once-daily versus twice-weekly terbinafine administration for the treatment of canine Malassezia dermatitis – A pilot study. Vet Dermatol. Vol. (23), pp. 418–479. Doi:10.1111/j.1365-3164.2012.01074.x
- Pinchbeck, L.R., Hillier, A., Kowalski, J.J., Kwochka, K.W. (2002). Comparison of pulse administration versus once daily administration of itraconazole for the treatment of Malassezia pachydermatis dermatitis and otitis in dogs. J Am Vet Med Assoc. Vol. (220), pp. 1807–1812. Doi: 10.2460/javma.2002.220.1807
- Guillot, J., Bensignor, E., Jankowski, F., Seewald, W., Chermette, R., Steffan, J. (2003). Comparative efficacies of oral ketoconazole and terbinafine for reducing Malassezia population sizes on the skin of Basset Hounds. Vet Dermatol. Vol. (14), pp. 153–157. Doi:10.1016/j. mmcr.2018.12.004
- Cavana, P., Petit, J.Y., Perrot, S. (2015). Efficacy of a 2% climbazole shampoo for reducing Malassezia population sizes on the skin of naturally infected dogs. Journal of Medical Mycology. Vol. 25(4), pp. 268–273. Doi:10.1016/j. mycmed.2015.10.004
- Chen, T.A., Hill, P.B. (2005). The biology of Malassezia organisms and their ability to induce immune responses and skin disease. Vet Dermatol. Vol. (16), pp. 4–26. Doi:10.1111/j.1365-3164.2005.00424.x
- Lee, Y.W., Byun, H.J., Kim, B.J., Kim, D.H., Lim, Y.Y., Lee, J.W., Kim, M.N., Kim, D., Chun, Y.J., Mun, S.K., Kim, C.W., Kim, S.E., Hwang, J.S. (2011). Distribution of Malassezia species on the scalp in Korean seborrheic dermatitis patients. Ann Dermatol. Vol. 23(2), pp. 156–161. Doi: 10.5021/ad.2011.23.2.156
- Shokri, H., Khosravi, A., Rad, M., Jamshidi, S. (2010). Occurrence of Malassezia Species in Persian and Domestic Short Hair Cats with and without Otitis Externa. J Vet Med Sci. Vol. 72(3), pp. 293–296. Doi: 10.1292/jvms.09-0421
- Gustafson, B.A. (1955). Otitis externa in the dog. A bacteriological and experimental study, 1 edn., Stockholm: Royal Veterinary College. 117 р. Available at: https://www. cabdirect.org/cabdirect/abstract/19552204211
- Baxter, M. (1976). The association of Pityrosporum pachydermatis with the normal external ear canal of dogs and cats', J Small Anim Pract. Vol. 17(4), pp. 231–234. Doi:10.1111/j.1748-5827.1976.tb06953.x.
- Crespo, M.J., Abarca, M.L., Cabanes, F.J. (1999). Isolation of Malassezia furfur from a Cat. J. Clin. Microbiol. Vol. 37(5), pp. 1573–1574. Doi:10.1128/JCM.37.5.1573- 1574.1999
- Guého, E., Midgley, G., Guillot, J. (1996). The genus Malassezia with description of four new species. Antonie Van Leeuwenhoek. Vol. 69(4), pp. 337–355. Doi:10.1007/ BF00399623
- Bond, R., Anthony, R.M., Dodd, M., Lloyd, D.H. (1996). Isolation of Malassezia sympodialis from feline skin. Journal of Medical and Veterinary Mycology. Vol. 34(2), pp. 145–147. Doi: 10.1080/02681219680000221
- Crespo, M.J., Abarca, M.L., Cabanes, F.J. (2000). Otitis externa associated with Malassezia sympodialis in Two Cats. J Clin Microbiol. Vol. 38(3), pp. 1263–1266. Doi:10.1128/JCM.38.3.1263-1266.2000
- Bond, R., Howell, S., Haywood, P. (1997). Isolation of Malassezia sympodialis and Malassezia globosa from healthy pet cats. Vet Rec. Vol. 141(8), pp. 200–201. Doi:10.1136/vr.141.8.200
- Ahman, S., Bond, R., Perrins, N. (2007). Carriage of Malassezia spp. yeasts in healthy and seborrhoeic Devon Rex cats. Medical Mycology. Vol. 45(5), pp. 449–455. Doi:10.1080/13693780701377170
- Hirai, A., Kano, R., Makimura, K., Duarte, E.R., Hamdan, J.S., Lachance, M.A., Yamaguchi, H., Hasegawa, A. (2004). Malassezia nana sp. nov., a novel lipid-dependent yeast species isolated from animals. Int J Syst Evol Microbiol. Vol. 54(Pt 2), pp. 623–627. Doi:10.1099/ijs.0.02776-0.
- Castell, G., Bellis, F.D., Bond, R., Cabañes, F.J. (2011). Molecular characterization of Malassezia nana isolates from cats. J Vet Microbiol. Vol. 148(2-4), pp. 363–367. Doi:10.1016/j.vetmic.2010.09.021
- Bond, R. (2009). Superficial veterinary mycoses. Clin Dermatol. Vol. 28(2), pp. 226–236. Doi:10.1016/j. clindermatol.2009.12.012
- Wagner, R., Schadler, S. (2000). Qualitative study of Malassezia species colonisation in young puppies. Vet Rec. Vol. 147(7), pp. 192–194. Doi:10.1136/vr.147.7.192.
- Matousek, J.L., Campbell, K.L., Kakoma, I., Solter, P.F., Schaeffer, D.J. (2003). Evaluation of the effect of pH on in vitro growth of Malassezia pachydermatis. Can J Vet Res. Vol. 67(1), pp. 56–59. PMCID: PMC227028 Available at:https://www.pubmed.ncbi.nlm.nih.gov/12528830/
- Colombo, S., Nardoni, S., Cornegliani, L., Mancianti, F. (2007). Prevalence of Malassezia spp. in feline nail folds: a cytological study. Vet Dermatol. Vol. 18(4), pp. 278–283. Doi:10.1111/j.1365-3164.2007.00592.x
- Cafarchia, C. (2007). Occurence and population size of Malassezia spp. in the external ear canal of dogs 57 nvvm.btsau.edu.ua Науковий вісник ветеринарної медицини, 2021, № 1 and cats both healthy and with otitis. Mycopathologia. Vol. 18(4), pp. 278–283. Doi:10.1007/s11046-005-0151-x.
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