You are here
Effect of vitamin c on indices system and antioxidant immunoreactivity calves vaccinated against salmonella
It is on the development and functioning of the immune system depends on resistance, which is often due to the effects of adverse environmental factors reduced. There is the development of immunodeficiency, as a result of disrupted the ability of the body to produce the required amount of antibodies for protection against infectious diseases. Feeding newborn calves ascorbic acid in the early adaptation period led to the growth rate at low glutathione levels of malondialdehyde, which showed positive enhancement of the level of antioxidant system. The decline in vitamin C and glutathione in plasma of calves at vaccination and revaccination was necessary in a young body needs this vitamin for immunization. The use of ascorbic acid as an immunomodulator calf-there with their immunization vaccine against salmonellosis caused increase of immune cells in their body.
Key words: vitamin C, immunity, calves, vaccination, salmonellosis, resistance, T- and B-lymphocytes, BABS, LABS, glutathione peroxidase (GPO), malondialdehyde (MDA).
1. Kvachev V.G. Immunodeficitnye sostojanija i ih korrekcija u sel'skohozjajstvennyh zhivotnyh / V.G. Kvachev, A.Ju Kasich // S.-h. bjul. – 1991. – № 2. – S. 105–114.
2. Fedorov Ju.N. Immunoprofilaktika boleznej novorozhdennyh teljat / Ju.N. Fedorov // Veterinarija. – 1996. – № 11. – S. 1–4.
3. Romanovych M.K. Reakcija organizmu teljat na nespecyfichni stymuljatory rezystentnosti / M.K. Romanovych // Veterynarna medycyna Ukrai'ny. – 1998. – № 7. – S. 38–39.
4. Gourman M.R.G. Evaluation of fagocytic cell funktion / M.R.G. Gourman // Clin. Lab. Immunol. – Washington, D.C. ASM Press. – 2002. – P. 265–273.
5. Komar V.I. Vodorastvorimye vitaminy v infekcionnoj patologii / V.I. Komar, V.S. Vasil'ev, N.K. Mojseenko. – Minsk: Nauka i tehnika, 1991. – 200 s.
6. Biohimichni osnovy normuvannja vitaminnogo zhyvlennja koriv. Vodorozchynni vitaminy / V.V. Vlizlo, B.M. Kurtjak, L.I. Sologub [ta in.] // Biologija tvaryn. – 2007. – T. 9, № 1–2. – S. 43–51.
7. Stolygevo N.S. Vlijanie vitamina S na immunologicheskuju reaktivnost' organizma / N.S. Stolygevo // Voprosy pitanija: material resp. nauch. konf. po voprosam pitanija, 16–17 sentjabrja 1952 g. – Riga, 1953. – S. 43–52.
8. Karput' I.M. Vlijanie vitamina S i antibiotikov na immunogenez / I.M. Karput' // Veterinarija. – 1974. – № 11. – S. 59–61.
9. Brigelius-Flohe R. Ascorbic acid, cell proliferation, and cell differentiation in culture / R. Brigelius-Flohe, L. Flohe // Subcell Biochem. – 1996. – Vol. 25. – P. 83–107.
10. Sakagami H. Modulation factors of radical intensity and cytotoxic activity of ascorbate (review) / H. Sakagami, K. Satoh // Anticancer Res. – 1997. – Vol. 17. – P. 3513–3520.
11. Ivchenko V.M. Metody imunologichnyh doslidzhen' v laboratorijah veterynarnoi' medycyny: metod. rekomendacii' dlja likariv-imunologiv laboratorij vet. medycyny / V.M. Ivchenko, N.I. Sahnjuk. – Bila Cerkva, 2009. – 82 s.
12. Laboratornye issledovanija v veterinarii: biohimicheskie i mikologicheskie: spravochnik / [Antonov B.I., Jakovleva T.F., Derjabina V.I. i dr.]; pod red. B.I. Antonova. – M.: Agropromizdat, 1991. – 287 s.
13. Moin V.M. Prostoj i specificheskij metod opredelenija aktivnosti glutationperoksidazy v jeritrocitah / V.M. Moin // Lab. delo. – 1986. – № 12. – S. 724–727.
14. Andreeva L.I. Modifikacija metoda opredelenija perekisi lipidov v teste s tiobarbiturovoj kislotoj / L.I. Andreeva, L.A. Kozhemjakin, A.A. Kishkun // Lab. delo. – 1988. – № 11. – S. 41–43.
15. Chumachenko V.E. Metodicheskie rekomendacii po opredeleniju estestvennoj rezistentnosti u sel'skohozjajstvennyh zhivotnyh dlja veterinarnyh specialistov / V.E. Chumachenko. – K., 1992. – 86 s.
16. Karput' I.M. Immunologija i immunopatologija boleznej molodnjaka / I.M. Karput'. – Mn.: Uradzhaj, 1993. – 288 s.
Attachment | Size |
---|---|
2013_11_fedorchenko_ua.pdf | 435.87 KB |